Reductil (sibutramine) is meant to aid weight loss in patients with a body mass index (BMI) of 30 or higher, and people with a BMI of 27 who also have other obesity related risk factors, such as high cholesterol or type 2 diabetes.
Sibutramine is sold under a variety of names; along with Reductil and Meridia, it is sold as Sibutrex, Sibuslim, Sibutral, Trimex etc.
Reductil contains the active ingredient 'sibutramine hydrochloride monohydrate' which is a type of anti-obesity medicine and works by affecting neurotransmitters in the brain.
Reductil prevents two of neurotransmitters (noradrenaline and serotonin) from being reabsorbed back into the nerve cells thus enhancing the feeling of fulfillment from eating, and making you feel satisfied after eating less food.
An appropriate diet and exercise programme is recommended while taking Reductil, so that you are able to maintain your new weight after you stop the treatment.
The most frequently observed side effects of Reductil include: a dry mouth, insomnia, nausea, constipation, joint or muscle pain, headache, menstrual cramps. Reductil may also trigger more serious side effects, though these have been noted less commonly: these include an increase in blood pressure and pulse, mood changes and depression.
Reductil is usually taken for a long time, up to one year. It should not be taken with other appetite suppressants.
Phentermine (adipex) is a stimulant that is similar to an amphetamine. It works by decreasing your appetite, increasing the amount of energy used by your body, by affecting certain parts of the brain. This medication is an appetite suppressant and belongs to a class of drugs called sympathomimetic amines.
It works by releasing norepinephrine in the brain, a neurotransmitter which reduces hunger by signaling a “fight of flight” response. The FDA recommends taking Phentermine for up to 12 weeks.
Phentermine is usually used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes.
Side effects associated with Phentermine are generally mild and tolerable. The most common side effects include: the possibility of insomnia, nervousness, irritability, increased libido in women, headache and diarrhea.
Do not use Phentermine or Reductil if you are pregnant or breast-feeding a baby.
You should not take Phentermine or Reductil if you have a history of heart disease, severe or uncontrolled high blood pressure, overactive thyroid, glaucoma, if you are in an agitated state, or if you have a history of drug or alcohol abuse.